Architecture of a K+ Channel Inner Pore Revealed by Stoichiometric Covalent Modification
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چکیده
منابع مشابه
Architecture of a K+ Channel Inner Pore Revealed by Stoichiometric Covalent Modification
Inwardly rectifying K+ channels bind intracellular magnesium and polyamines to generate inward rectification. We have examined the architecture of the inner pore of Kir2.1 channels by covalently attaching a constrained number (from one to four) of positively charged moieties of different sizes to the channel. Our results indicate that the inner pore is formed solely by the second transmembrane ...
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ژورنال
عنوان ژورنال: Neuron
سال: 1999
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)80711-4